Finally, the panel came back: I had a severe vitamin B12 deficiency
Vitamin B12 deficiency anemia due to intrinsic factor deficiency
The NHS treatment pathway and the 2024 NICE guideline both assume B12 injections are given in a clinical setting against a confirmed deficiency, not self-sourced and self-administered
In addition to limited absorption via the IF, the intake of high-dose supplements leads to passive diffusion, i.e., the vitamin can freely enter the bloodstream without IF binding and receptor uptake
Vitamin B12 Supplements Its vital to treat a B12 deficiency to avoid permanent nerve damage, among other problems
This led to its popularity for metabolism and body composition, with users reporting sustained weight loss and energy gains