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Thermal proteome profiling strategy identifies CNPY3 as a cellular target of gambogic acid for inducing prostate cancer pyroptosis

Additional research is exploring its utility in examining selective senescent cell vulnerability, apoptosis signaling mechanisms, and the molecular regulation of cell survival under chronic stress conditions

Contact Dermatitis 35(3):175176 Mayorga C, Celik G, Rouzaire P, Whitaker P, Bonadonna P, Rodrigues-Cernadas J, Vultaggio A, Brockow K, Caubet JC, Makowska J et al (2016) In vitro tests for drug hypersensitivity reactions: an ENDA/EAACI Drug Allergy Interest Group position paper

Widespread rashes, hives, or breathing difficulties indicate serious allergy requiring immediate discontinuation and medical attention

6) Hematologic and immune reactions (rare but real) Serious skin reactions (SJS/TEN) and anaphylaxis are rare but dose-independent idiosyncrasies

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