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Interventions that combine dietary modification, increased and regular physical activity, and behaviour therapy are the most effective at improving health outcomes

Structurally, semaglutide is an acylated peptide analogue of native GLP-1

weight, circumferences), and BC using tools such as bioelectrical impedance vector analysis (BIVA), nutritional tissue ultrasound (to assess subcutaneous fat and muscle tissue), and handgrip strength testing

Wharton S, Lingvay I, Bogdanski P, et al

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148 These drugs act by simultaneously targeting three different agonists GLP-1R, the GIPR, and the GCGR