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Hydrate Well: Drink plenty of water to help minimize potential side effects like flushing and headaches

Progestins such as the levonorgestrel IUD or depot medroxyprogesterone can shrink lesions and eliminate periods, with the IUD effective for up to 5 years

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Any consideration of adding a GLP-1 agonist must occur under close rheumatologist supervision, particularly if weight loss or glycemic goals are also present