If you do not eat oily fish at least twice a week, a high-quality fish oil supplement is a wise addition
If nausea is severe, do not assume it is only from the GLP-1 medication
Case 2 A 74-year-old white man with a history of type II diabetes presented with an itchy rash on the bilateral flanks and lower abdomen for 3 weeks duration
While direct head-to-head comparisons in randomized clinical trials are limited, real-world evidence and observational studies help supplement the lack of direct head-to-head clinical trial data, offering important context for clinical decision-making
The results showed that in the SUSTAIN 3, 7, and 10 trials, nausea/vomiting during dose escalation or throughout treatment contributed minimally ( 65 years), and baseline cardiovascular risk profile (prior myocardial infarction or stroke vs no prior MI or stroke, and established cardiovascular disease vs CV risk factors alone, including chronic kidney disease)
Standard RA treatment with disease-modifying drugs like methotrexate or biologics has proven efficacy, while GLP-1 drugs lack established disease-modifying effects for rheumatoid arthritis