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The PGC-1-NRF1-FUNDC1 signaling pathway plays an important role in the balance between mitophagy and mitochondrial biogenesis (Liu L

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By contrast, doxorubicin shows negligible oral uptake ("Non-Bioavailable", Table 4) and poor intestinal absorption ("Non-Absorbed", Table 4), consistent with its clinical use exclusively via intravenous routes 68

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