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For high-risk patients or those with documented decline despite optimal lifestyle measures, referral to clinical trials of emerging anabolic/anti-catabolic therapies is appropriate

Notably, vincristine showed minimal influence on the proteomic landscape altered by MitoQ + DPI combination

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These data demonstrate that metformin, significantly radiosensitises radiosensitive HCT116 cells and radioresistant SW837 cancer cells at a clinically-relevant dose of 1.8 Gy

Again, please be aware that this new Guideline is aimed at the current Covid-19 pandemic