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More recently, it has been demonstrated that 1012 weeks of dietary supplementation with Endocalyx, which contains high-molecular weight HA and other glycocalyx components, restores the glycocalyx and ameliorates age-related vascular dysfunction in aged mice (135)

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Autoimmunity (2020) 54(1):1322

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This variation has been associated with increased TNF- production and a more pronounced inflammatory response, which may contribute to a higher baseline level of systemic inflammation and increased sensitivity to inflammatory triggers