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The Pharmaceutical Benefits Advisory Committee will need to consider the ready availability of incretin analogues for the management of obesity against the long-term health and other costs of obesity to the Australian community

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Absolute contraindications to GLP-1 receptor agonists include: Personal history of medullary thyroid carcinoma Family history of medullary thyroid carcinoma Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Pregnancy (for weight management indications) Severe gastrointestinal disease, including gastroparesis Patients should be specifically questioned about these conditions during pre-treatment evaluation

Each component works synergistically to enhance your body's ability to use fat for energy

The current NICE guidance on B12 and folate deficiency sets this out clearly

Early data from amycretin showed up to 13.1% weight loss in just 36 weeks of a phase 1/2 trial, with the weight loss curve still descending steeply