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Without ROS, the acrosome reaction would not be triggered, and the sperm would be unable to fertilize the egg

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Further research is needed to elucidate the basic mechanism underpinning T and B-cell recruitment into an immune response, to examine antibody affinity maturation and to identify the determinants of the immunodominance hierarchy for T and B-cell epitopes, which ultimately may enable vaccine antigens to be rationally designed to induce broadly targeted immunity

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Cells were washed in PBS and centrifuged (200 g , 5 min)

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