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(2012) it was observed that prenatal second hand smoke exposure was associated with a 52% increased risk of wheeze in children aged 5 to 18 years (Odds Ratio (OR) = 1.52, 95% CI = 1.231.87, I2 = 21.1%, 5 studies) (Burke, et al., 2012)

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Long-term exposure to cigarette smoke impairs lung function and increases HMGB-1 expression in mice

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I agree with Big Train on Tobacco Reviews that this is an almost unique blend and, as such, will deeply appeal to a smaller sub-set of smokers, and not gain a wide audience