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GLP-1 activity also helps the pancreas release insulin when blood sugar is high

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To avoid this pitfall, we here use PAR2-mutant mice (PAR2-G37I and PAR2-R38E) that retain activation-independent signaling receptor platforms involving PAR2, while abolishing cleavage sensitivity to specific proteases (21, 22, 30, 31)

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Structureless areas Structureless areas are caused by the obliteration of the follicular openings