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Its a simple variable to control, but one that is often overlooked

Especially its use in chronic Q-fever, when prolonged relatively high doses are given nowadays in combination with hydroxychloroquine, prescribers and patients should be aware of this side effect

Watabe S, Makino Y, Ogawa K, Hiroi T, Yamamoto Y, Takahashi SY

The use of lactate for energy has been proposed to occur within the mitochondria where it can be oxidized to pyruvate by mitochondrial LDH which localizes to the inner mitochondrial membrane