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Their presence would indicate a problem with injection technique, preparation, or in rare cases, individual sensitivity that should prompt a review of the protocol and professional consultation

doi: 10.1073/pnas.1000097107 45 Juarez-FernandezMPorrasDGarcia-MediavillaMVRoman-SaguilloSGonzalez-GallegoJNistalEet al

In general a Cohen's d effect size between 0.2 and 0.4 is small, between 0.5 and 0.7 is medium and 0.8 or above is large

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Glutathione is a naturally occurring antioxidant with minimal side effects at therapeutic doses, and tirzepatide has no known interactions with antioxidant supplementation