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This browning is mediated through multiple pathways including SIRT1/PGC-1 activation, increased expression of thermogenic genes (UCP1, PRDM16, PPAR), and enhanced mitochondrial biogenesis

Improved cognitive function: Patients often describe feeling as though a mental fog has lifted, reporting improved memory, concentration, and mental clarity

One of Maedis daughters was born with a syndrome, is intellectually disabled and a self-advocate of ILO

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