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HDLs primary receptor for cholesteryl ester (CE) uptake, scavenger receptor BI (SR-BI), is also a bidirectional free cholesterol transporter in that it facilitates the efflux and influx of free cholesterol between cells and mature HDL (693-695) (Figure 2)

Health Canada approves Wegovy for the treatment of adults with obesity

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To verify clinical significance, more human research is required (174)

While it may resemble melasma or dark spots, it is actually a type of acquired dermal pigmentation, not a true dark spot

Portion sizes may need adjustment based on individual tolerancea half-cup of cooked oatmeal may suffice where a full cup was previously consumed