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This discrepancy may be due to AD-related injury at later disease stages, emphasizing the need for clinical trials initiated prior to dementia onset

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Conclusions and future prospects The findings of this systematic literature review underscore the potential protective effects of Met and GSH alone and in combination with other compounds to improve sperm parameters, testicular dysfunction, gonadotropin hormones, testicular antioxidants, reproductive health, and fertility

Since D2HG and L2HG are indistinguishable in standard LC-MS, to determine which 2HG enantiomer(s) is affected, we adapted a chiral N-(p-toluenesulfonyl)-L-phenylalanyl chloride (TSPC) derivation followed by liquid chromatography with tandem mass spectrometry (LC-MS/MS) analysis 24,40

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