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J Med Chem 58:73707380 Lee TS, Park EJ, Choi M, Oh HS, An Y, Kim T, Kim TH, Shin BS, Shin S (2023) Novel LC-MS/MS analysis of the GLP-1 analog semaglutide with its application to pharmacokinetics and brain distribution studies in rats

Body weight and adiposity models: In diet-induced obesity (DIO) mouse models, retatrutide demonstrated pronounced effects on body weight trajectories over multi-week observation periods compared with vehicle controls

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These investigators speculate that mammalian intestinal iron transport is analogous to the yeast iron uptake process (Harford et al., 1994)

Possibilities include a reduction in hemoglobin A1C, LDL cholesterol, blood pressure, and weight