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However, when adjusting for publication bias found in ALT and AST, there was no significant difference in estimates between GLP-1RA and TZD for both ALT and AST

Our analysis indicates that there is no significant influence from unmeasured confounding variables (E-values for the point estimates [lower limits of the CI] were 2.90 [3.32), 1.54 [1.92), and 2.09 [2.39) for mortality, MACE, and MAKE, respectively)

Semaglutide's Indian patent expired on 20 March 2026

Benefits beyond diabetes and weight loss, include a 30% reduction in the risk of heart attacks and strokes

Retatrutide may redefine it

Consult your doctor if you notice any such effects while taking it