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Because niacinamide is both a pigment inhibitor and an anti-inflammatory, it not only helps reduce hyperpigmentation but also soothes redness or irritation from shaving

Through caffeine inhibition of adenosine receptors, the drug increases central respiratory drive and stimulates respiratory drive through its ability to increase pulmonary response to carbon dioxide in the medullary system

He has shared his personal supplement regimen, detailed in his book "Lifespan" and various interviews

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PUFA, Polyunsaturated fatty acids

Reference per Shay 2009 mechanistic review: American Diabetes Association Professional Practice Committee