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The supernatant was collected after centrifugation at 1000 g for 5 min, and 0.1 mL of the supernatant was mixed with 1.7 mL phosphate buffer (0.1 M, pH 8) and 0.1 mL Ellmans reagent
It works by mimicking the action of incretin hormones, which enhance insulin secretion in response to meals, suppress glucagon release, slow gastric emptying, and reduce appetite
doi:10.1056/NEJMoa1607141 Pi-Sunyer X, Astrup A, Fujioka K, et al
According to the case report, published in JAAD Case Reports, researchers described the lesions as "initially erythematous and pruritic reactions [that] subsequently progressed into asymptomatic chronic hyperpigmented patches with an erythematous border." Physical examination revealed "multiple dusky hyperpigmented round patches with erythematous borders on her buttock and abdomen." A 4-mm punch biopsy from the right buttock demonstrated "lichenoid interface dermatitis