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Going from the inside to the outside, we find a microclimate consisting of the unstirred water layer, glycocalyx, and mucus layer which prevent bacterial adhesion by physical barrier provided by the glycocalyx and mucus and by the secretion of antimicrobial proteins (AMPs) and immunoglobulin A (IgA)

To understand how this evolving market might play out, this paper will address the following questions: What is the current state of the incretin mimetic market in diabetes and obesity, and how did we get here