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If LDL-C is at target (generally below 70 mg/dL for high-risk ASCVD patients per ACC/AHA 2019 guidelines), there is no phenotypic signal of interference

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[8] Similarly, individuals with thyroid disorders should be aware that ALA might affect thyroid hormone levels

Scand J Gastroenterol 15(1):6163 [DOI] [PubMed] [Google Scholar] Walle UK, Walle T, Bai SA, Olanoff LS (1983) Stereoselective binding of propranolol to human plasma, alpha 1-acid glycoprotein, and albumin