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A 2025 safety review found that at typical supplement doses (around 500 mg/day over several weeks), gastrointestinal symptoms like flatulence and loose stools were the most common effects and they were transient, usually resolving on their own (Alzahrani et al., 2025)

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The Manufacturing Challenge Despite the promising revenue forecasts, the GLP-1 market faces a significant bottleneck: manufacturing capacity

ORCID: Affiliation: 14 International Joint Research Center on Purinergic Signalling, School of Health and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, Sichuan, China 15 Tianfu Jincheng Laboratory, Chengdu 610212, Sichuan, China These authors contributed equally to this work

(~) unrestricted diet supplemented with tyrosine