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GLP-1R agonists with prolonged half-life (generated by amino acid substitutions and linkage to a fatty acid, the Fc region of IgG4 or albumin [16]) have been developed to treat type 2 diabetes [17]

The FDA approves medications to be used according to manufacturers exact instructions

Clin Ther 29(1):139153 Buse JB, Rosenstock J, Sesti G, Schmidt WE, Montanya E, Brett JH et al (2009) Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6)

This is because aging adults often develop problems with the acids and stomach enzymes needed to process the vitamin

Gut Microbes (2014) 5:48593

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