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Dosing is extrapolated from preclinical models [1] [6]

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It doesn't just stay in one place

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Based on observations, you might need to titrate the dose up or down

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Growth response to rhIGF-I 80 microg/kg twice daily in children with growth hormone insensitivity syndrome: relationship to severity of clinical phenotype

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It's typically diagnosed through a complete blood count (CBC) and peripheral blood smear, which reveals the enlarged red blood cells

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The fix: inject 1-2 cm below the kneecap, directly over the patellar tendon

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