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Cardiovascular benefits have been demonstrated in clinical trials for specific GLP-1 receptor agonists, with liraglutide, semaglutide, and dulaglutide showing reductions in major adverse cardiovascular events in patients with established cardiovascular disease or high cardiovascular risk

Microfilaments, the thinnest of these filaments, are involved in cell morphology and motility and consist of actin filaments (F-actin) that are polymerized from monomeric globular actin (G-actin)