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Alterations resulting from METex14 mutations are marked by the partial removal of the parallel membrane configuration or hindered attachment to the E3 ubiquitin-protein ligase CBL, which impedes MET protein ubiquitination and self-degradation, thereby extending the activation of subsequent signals [23, 24]

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Melanin is important for your skin to mask it from harmful UV rays, which can cause several skin disorders 1,2

Thomas Ruiz, a board-certified OB/GYN and lead OB/GYN at MemorialCare Orange Coast Medical Center in Fountain Valley, CA, about this study