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These symptoms are most common during therapy initiation and dose escalation, and they may improve over time as tachyphylaxis to the gastric-emptying effect develops in some patients
This activation of the PI3K pathway could trigger Protein Kinase B (Akt), a potential enzyme within this pathway that may influence the movement of glucose transporters to the plasma membrane, potentially increasing the uptake of glucose by cells
PLOS ONE , 5(9), e12684
GO also has biomedical applications
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