McGowan says this is likely due to genetic and physiological mechanisms driving excess weight, adding that when stopping these medications, people experience a rapid return of their hunger
ANDREW HUBERMAN: Well, I met you 10 years ago
You should not take this medication if you: Are allergic to metoprolol, any beta blocker, or any ingredient in the medication Have severe bradycardia (slow heart rate) Have second-degree or third-degree heart block (interference with electrical signals that tell your heart when to beat) Are in cardiac shock (a life-threatening emergency where the heart cannot pump enough blood and oxygen to the brain and other organs) Have decompensated heart failure Have sick sinus syndrome (heart rhythm problems caused by the hearts pacemaker), unless you have a permanent pacemaker Have a severe peripheral arterial circulatory disorder (a narrowing or blockage of the vessels that carry blood from the heart to the legs) Metoprolol may not be appropriate for people with certain other medical conditions
[ [PMID: 37513906] [ [PMID: 20550725] et al
The 2026 reclassification of several peptide categories in the US and UK research framework has clarified their status as research-use compounds, distinguishing them from controlled pharmaceuticals while maintaining the standard research-use designation
Symptoms include diarrhea (dumping), abdominal cramps, vomiting, and fatigue and dizziness after eating foods containing sugar