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In a subsequent mechanistic study, they found that MET first activated the MAPK signaling pathway, followed by the activation of the downstream NF-B-mediated p65 transcription factor, which interacted with the proximal region of the PD-L1 promoter to promote PD-L1 expression [133]

Blom AM, Kask L, Ramesh B, Hillarp A

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Serious Side Effects Gastrointestinal Issues: Reports indicate the possibility of severe stomach problems