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Best injection sites: abdomen (preferred) or upper thighs

While knee injections are typically safe and risk of complication is quite low, there are some potential adverse effects

It has several effects, including stimulating insulin secretion (to lower blood sugar) and promoting satiety (the feeling of fullness)

The international clinical guidelines place dietary glycemic-load management, regular movement (150 to 250 minutes of moderate exercise per week), and adequate sleep as first-line interventions (Teede et al

Akins, N

Clinicians also look at cardiovascular history, blood pressure, blood lipids and glucose, liver and kidney function, existing medications, and any history that suggests higher risk for pancreatitis or gallbladder disease