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Nat Metab 3 , 297298 (2021)

Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show

In preclinical studies, the combination of PLK1 inhibitor Volasertib (intravenous injection, 30 mg/kg) and HDACi Belinostat (intraperitoneal injection, 50 mg/kg) significantly inhibited tumor growth in a DLBCL/MCL mouse model by synergistically inducing DNA damage and downregulating c-Myc (104)

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