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For example, meningeal T cells, which secrete high levels of IL-17A, play a crucial role in modulating anxiety-like behaviors by signaling to neurons with IL-17RA within the medial prefrontal cortex (mPFC) [112]

Evidence Gap Long-term (multi-year) outcomes data is still maturing

103 The absence of obesity-associated resistance to the anorectic properties of PYY 3-36 makes it an attractive target for treatment

Suzuki H, Mashimo K