Its also one of the more affordable options, but it requires more frequent administration
Originally marketed for diabetes management, the drug is now used for weight loss in teens and adults
Vitamin E helps support healthy-looking, hydrated skin
Folate is the core one-carbon donor and it acts synergistically with vitamin B 12 , vitamin B 6 and riboflavin which are cofactors for some of the key enzymes in OCM (Fig
Further medicinal chemistry optimization to improve structure activity relationship and potency as well as safety and toxicity, pharmacokinetic (bioavailability, half-life and biodistribution) and rodent in vivo studies will follow to determine the compounds potential to become suitable candidates for further development
OTC alternatives are unlikely to address these conditions with sufficient potency, and delaying evidence-based treatment may prolong metabolic complications