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The same clinical rules apply to compounded semaglutide as they do to branded Wegovy

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Data availability Data will be available in a public repository at Change history 10 July 2025 A Correction to this paper has been published: References Ostrom QT, Price M, Neff C, Cioffi G, Waite KA, Kruchko C, et al

The clear influence of therapeutic GLP-1 analogs on the physiology of the digestive system as well as the stability and diversity of the gut microbiota deserves special attention because disorders of the gut-brain axis homeostasis also appear to be an important, although so far somewhat understudied factor, which may lead to the development of depression