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This led to a reduction in the expression of the fibrosis genes actin-alpha-2 (ACTA2) and collagen-type-1-alpha-1 (COL1A1) in the kidneys, suggesting that the inhibitor may have therapeutic promise for treating renal fibrosis[83]

The outcome of such computational pipelines is reproducibility: any researcher can replicate the virtual model and compare it with experimental spectra, ensuring transparent analytical validation

During the inflammatory phase, it reduces excess inflammation while preserving the response needed to clear debris

The effect appears to be related to curcumin's ability to reduce oxidative stress and inflammation in the intestinal cells that produce GLP-1

New Journal of Physics , 15 , 015008

RING finger ubiquitin protein ligases: implications for tumorigenesis, metastasis and for molecular targets in cancer