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Contact your GP or seek medical advice if you experience: Diarrhoea lasting more than four weeks (the UK clinical definition of chronic diarrhoea) Blood or mucus in the stool Significant abdominal pain or cramping that does not resolve Signs of dehydration , including dark urine, dizziness, dry mouth, or reduced urine output Unintentional weight loss that exceeds your dietary goals Nocturnal diarrhoea (being woken from sleep by the need to open your bowels) Symptoms accompanied by fever or vomiting For severe dehydration, persistent bloody stools, or signs of systemic illness, contact NHS 111 or attend your nearest urgent care or emergency department

Low folate status is a risk factor for development of neural tube defects in the developing foetus

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As of early 2026, over 3,000 lawsuits are pending against the manufacturers of GLP-1 drugs