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Large-scale human studies evaluating long-term exposure, systemic absorption, and potential adverse effects remain limited

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GHK-Cu is an endogenous peptide that the body produces on its own

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Gibbs et al., 1968

Selective therapeutic targeting of tumor-derived cells expressing Tie-2 could disrupt the vasculature and eradicate the tumor, leading the authors to conclude that glioma stem cell derived endothelial cells contributed to vascularization of glioma [59]