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Results: After 1 year of treatment using TPE with 5% albumin, UCT-MSC-EXs, Semax and Epitalon, the patients biological age was reduced by 7.9 years (from 75.93 to 68.03), and his telomere length increased from 6.45 to 6.59 kb

There is an urgent need to develop novel topical formulations of berberine and conduct preclinical or clinical studies to evaluate the efficacy of transdermal delivery systems for weight management