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Anti-drug antibodies may develop against therapeutic peptides, particularly those that differ structurally from endogenous human peptides

[DOI] [PMC free article] [PubMed] [Google Scholar] 57.Zhang L, et al

Quick Answer: GLP-1 probiotics typically cause mild gastrointestinal side effects such as bloating, gas, and temporary digestive changes, though serious risks exist for immunocompromised individuals

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The molecule is building up, not peaking

Two primary areas emerge from the data as being critical for longevity: gut barrier integrity and metabolic function, especially as it relates to GLP-1