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doi: 10.1016/j.molmet.2018.09.009 [DOI] [PMC free article] [PubMed] [Google Scholar] 62.Mclean BA, Wong CK, Campbell JE, et al

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Hypertrophic adipose tissue is associated with immune cell recruitment, increased basal fatty acid release, pro-inflammatory cytokine release, hypoxia, necrotic-like abnormalities, fibrosis, decreased adiponectin, impaired insulin sensitivity, and insulin-dependent glucose uptake related to a defect in GLUT4 trafficking (Choe et al., 2016)