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Relevant laboratory evaluation may be considered based on medical history and clinical judgment

Drugs for neuropathic pain, such as gabapentinoids, serotoninnorepinephrine reuptake inhibitors, tricyclic antidepressants, alpha-lipoic acid, sodium channel blockers, and topical capsaicin, are used for the management of painful DPN

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Diabetes contributes to structural and electrical changes in the heart, increasing susceptibility to arrhythmias

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