When GLP-1 medications reduce intrahepatic fat and glycogen by 40 to 50% (as multiple trials have shown), DXA reads that as lean body mass loss
Expected 12-month results include 15 to 22% body weight loss (50 to 75 pounds for a 300-pound person), 5 to 8 inch waist circumference reduction, major improvement in mobility and physical function, and often dramatic improvement or resolution of obesity-related health conditions including sleep apnea, fatty liver disease, and joint pain
"The two therapies may work best in combination, but we're still trying to figure out the best sequence and timing," he adds
Use of silver sulfadiazine cream, medical grade honey, and soft silicone dressings can be helpful in these settings
Retatrutide essentially amplifies this natural satiety signal, making it last longer and feel stronger than what your body produces on its own
Over-the-counter antidiarrheal medications like loperamide can be used judiciously for diarrhea (avoiding use if fever, blood in stool, or infection is suspected), though patients should consult their healthcare provider before regular use
