166 A recent study reported that S-nitrosylation altered AAT to a proinflammatory protein, which facilitated the inflammatory state of macrophages by upregulating proinflammatory molecules and the activation of MAPK signalling pathways
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Another study suggested that an oral dose of 1,200 mg of lipoic acid in subjects with multiple sclerosis could help achieve serum lipoic acid concentrations similar to those found to be therapeutic in mice (96)
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