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According to the American Diabetes Association, prediabetes can be defined by a condition of impaired fasting glucose, characterized by a fasting blood glucose concentration between 100 mg/dL and 125 mg/dL and/or a condition of impaired glucose tolerance, characterized by a 2-hour blood glucose concentration 140 mg/dL following an oral glucose tolerance test (56)

Notably, LA supplementation can also alter circadian rhythms

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NRF-2 responds to inflammatory-cell and tissular stimuli with pleiotropic effects that are not yet well defined

The inclusion of anticholinergics drugs, such as tiotropium, in the treatment of asthma has been supported by medical consensus since 2016

doi: 10.3892/etm.2019.7630 145 BretscherPA