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doi: 10.1038/s42003-021-01652-x

It imitates the glucagon-like peptide-1, a hormone that curbs the appetite, reducing food intake

Retatrutide is in Phase 3 clinical trials through Eli Lilly, and cagrilintide is in Phase 3 trials through Novo Nordisk (both as monotherapy and as part of CagriSema)

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No posee homlogo conocido en la naturaleza, lo que lo convierte en una molcula nica en el panorama de los pptidos bioactivos

The gene expression profiles in animal models of T2DM, such as the ZDF rat, is consistent with gene expression profiles of humans with T2DM [8], making this a suitable model to explore the global gene expression effects of diet in the ZDF rat