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10.1016/j.redox.2018.01.008 Redox

Human clinical application is still early, but the gene-level mechanism is well-documented

The readout Im watching next is the Novo Nordisk semaglutide MDD programs interim data, expected in late 2026 specifically whether the protocol captures anhedonia and reward-processing endpoints with enough granularity to detect the worsening signal the Swedish investigators flagged

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It could be speculated that this increased discontinuation rate vs all comparators, including GLP-1 RAs, may be possibly attributed to the severity of gastrointestinal adverse events experienced with tirzepatide 15 mg, considering that the incidence of gastrointestinal adverse events was similar between tirzepatide and GLP-1 RAs

If one does not have enough of this anti-oxidant in their bodies, free radicals will cause the entire body to age