Despite adequate membrane permeability, this low solubility places luteolin within a Biopharmaceutics Classification System (BCS) class IItype compound, where dissolution (not permeability) is the primary barrier to oral uptake ( 4 Luteolin in female reproductive disorders Luteolin has been investigated across a wide spectrum of female reproductive conditions, ranging from endocrine-metabolic dysfunctions to inflammatory, fibrotic, infectious, and malignant disorders
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*Correspondence: LongTao Liu [email protected] Wu [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Lipids in Cardiovascular Disease, a section of the journal Frontiers in Cardiovascular Medicine Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers