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FDA has also documented compounding-specific concerns about identity, impurities, and safety

Shisler JL, Senkevich TG, Berry MJ, Moss B

They are preferentially incorporated at low concentrations in triple combination therapies for melasma, such as Kligman ones (containing dexamethasone or fluocinolone acetonide), to reduce irritation caused by other components

Why injection rather than oral supplements

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